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eSpOT-ON Nuclease (High-Fidelity Cas9 mRNA)

United States

Engineered high-fidelity Cas9 mRNA for therapeutic genome editing with superior on-target activity and minimal off-target effects. Validated across human cell lines including iPSCs for cell and gene therapy applications.

Manufactured by

United States

Synthego develops scalable solutions for CRISPR research, molecular biology, and diagnostic workflows, serving the cell and gene therapy sector. The company specializes in custom CRISPR gene editors available in mRNA and protein formats designed for clinical applications, along with engineered cytosine base editors that eliminate double-strand breaks to enhance safety in therapeutic development. Synthego offers rapid, high-yield protein production capabilities using controlled, scalable systems independent of live cell culture. These solutions enable researchers and manufacturers to accelerate development of advanced therapeutics with improved fidelity and manufacturing flexibility.

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