Streptavidin-coated Magnetic Nanoparticles (100-300 nm)

Streptavidin-coated magnetic microspheres for biotin-specific binding in diagnostic assays. Enables indirect conjugation of antibodies, antigens, and haptens to microsphere surfaces for detection applications.

Streptavidin is a protein produced by Streptomyces avidinii and isolated by purification from fermentation broth. It consists of four identical subunits, each bearing an active binding site for biotin, and shows predominantly one single band in SDS PAGE. The protein is useful in combination with biotinylated antibodies, fluorescence applications, Western and Southern blotting, purification using immobilized streptavidin, and DNA/RNA analysis methodologies. Streptavidin is non-glycosylated and does not react unspecifically with endogenous lectins when used in assays on cells and tissues. It is available as a lyophilized format with activity >13 U/mg and purity of SDS - 1 band (non-reduced), with a stability of 3 years when stored dry at -20 °C.

Magnetic microspheres optimized for immunoassay applications including sandwich, competitive, and capture formats. High surface area and stable coating ensure reproducible results across multiple assay platforms.